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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RPS6KB2 All Species: 38.79
Human Site: S370 Identified Species: 60.95
UniProt: Q9UBS0 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UBS0 NP_003943.2 482 53483 S370 T R Q T P V D S P D D T A L S
Chimpanzee Pan troglodytes XP_001172909 482 53404 S370 T R Q T P V D S P D D T A L S
Rhesus Macaque Macaca mulatta XP_001117937 512 56562 S397 T R Q T P V D S P D D T A L S
Dog Lupus familis XP_851971 482 53401 S368 T R Q T P V D S P D D T A L S
Cat Felis silvestris
Mouse Mus musculus Q9Z1M4 485 53520 S370 T R Q T P V D S P D D T A L S
Rat Rattus norvegicus P67999 525 59113 S394 T R Q T P V D S P D D S T L S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509850 482 54026 S351 T R Q T P V D S P D D S T L S
Chicken Gallus gallus P18652 752 84421 S381 T S R T P K D S P G I P P S A
Frog Xenopus laevis P10665 733 82620 S363 T S R T P K D S P G I P P S A
Zebra Danio Brachydanio rerio Q6PFQ0 740 83378 D367 F T A K T P K D S P G I P P S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V3I5 1207 137026 L1001 E N A P P L P L P E E Y Y S E
Honey Bee Apis mellifera XP_395876 456 51514 P345 V I S R K L E P P F R P T L A
Nematode Worm Caenorhab. elegans Q21734 784 88102 S405 T K R T P K D S P A L P A S A
Sea Urchin Strong. purpuratus XP_781234 487 53968 S375 T K Q T P V D S P D D S M L S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q39030 471 53019 L359 K I K L P Q F L S N E A H A L
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 91.8 95 N.A. 92.9 65.7 N.A. 70.9 30 30.5 30.2 N.A. 21.1 56.8 29.9 60.9
Protein Similarity: 100 99.7 92.5 96.6 N.A. 95 76 N.A. 80.9 42.8 42.5 43.2 N.A. 28.3 70.7 43.1 74.5
P-Site Identity: 100 100 100 100 N.A. 100 86.6 N.A. 86.6 40 40 6.6 N.A. 13.3 13.3 46.6 80
P-Site Similarity: 100 100 100 100 N.A. 100 93.3 N.A. 93.3 53.3 53.3 6.6 N.A. 33.3 33.3 66.6 93.3
Percent
Protein Identity: N.A. N.A. N.A. 39.4 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 57.2 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 14 0 0 0 0 0 0 7 0 7 40 7 27 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 74 7 0 54 54 0 0 0 0 % D
% Glu: 7 0 0 0 0 0 7 0 0 7 14 0 0 0 7 % E
% Phe: 7 0 0 0 0 0 7 0 0 7 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 14 7 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % H
% Ile: 0 14 0 0 0 0 0 0 0 0 14 7 0 0 0 % I
% Lys: 7 14 7 7 7 20 7 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 7 0 14 0 14 0 0 7 0 0 60 7 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % M
% Asn: 0 7 0 0 0 0 0 0 0 7 0 0 0 0 0 % N
% Pro: 0 0 0 7 87 7 7 7 87 7 0 27 20 7 0 % P
% Gln: 0 0 54 0 0 7 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 47 20 7 0 0 0 0 0 0 7 0 0 0 0 % R
% Ser: 0 14 7 0 0 0 0 74 14 0 0 20 0 27 60 % S
% Thr: 74 7 0 74 7 0 0 0 0 0 0 34 20 0 0 % T
% Val: 7 0 0 0 0 54 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 7 7 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _